Sunday 3rd May 2009

Hi All,

Mixed week this week.

I had and still have high-hopes for the new drug regime. It certainly helped me in the first part of the week with definitely reduced nausea.

On Wednesday, I was recommended to double the dose to try and get rid of the last traces of sickness, but when I did this I fell foul of one of the main side-effects (no, no boobs yet!). The drug has a sedative effect which wasn't affecting me when I was on the 1.5mg dose, but when I upped to 3mg I found that it made me really groggy in the mornings and unable to get out of bed. It also didn't seem to improve the nausea symptoms any more.

I have since reverted to the lower dose, but yesterday and today I felt a bit pants most of the time. Last night I had a bad dose of diarrhoea for the first time in ages, and all day today I've been on the verge of nausea.

Unfortunately, now I only have the one drug, if I have something to eat or drink which sets me off, I've got nothing extra I can take to help me, which is putting me off my supplement drinks even more as they tend to trigger the nausea.

So all in all a mixed bag this week. Hopefully things will settle down again now I've lowered the dose. I might try somewhere in between like 2mg to see if that helps, but its just yet more experimentation.

I was told that it would take months and maybe up to a year before I got used to my diet etc, and I'm now starting to understand what they meant :(

On the better news front, I have the results from the specialist histology that was performed on my surgery sample by an endocrine tumour specialist. The good news is that she agreed completely with the original findings, so there are no more surprises. They will discuss my case on the 20th May at a specialist meeting, but the expectation is that everything will stay the same going forward. Nothing new to get stuck into, but nothing untoward either.

So everything generally ok, but still the problems with nausea, tiredness, and weightloss to contend with, which is going on far too long for my liking. Hopefully some better news next week when the drugs settle down.

Cheers,

Colin.